Statistics in Oncology Series
- Biomarkers have various applications including disease detection, diagnosis, prognosis, prediction of response to intervention, and disease monitoring. In this era of precision medicine, having validated biomarkers to inform clinical decision making is more important than ever. In this article, we discuss best the practices and potential issues in biomarker discovery and validation. We encourage team science partnerships to bring cutting-edge discovery from bench to bedside, leading to improved patient care and outcomes.
- Statistical methods are essential in medical research. They are used for data analysis and drawing appropriate conclusions. Clarity and accuracy of statistical reporting in medical journals can enhance readers’ understanding of the research conducted and the results obtained. In this manuscript, we provide guidelines for statistical reporting in medical journals for authors to consider, with a focus on the Journal of Thoracic Oncology.
- The Journal of Thoracic Oncology (JTO) is excited to introduce a series of brief articles on various statistical topics in the journal this year, starting with the current issue. As the mission of the JTO is to be the “primary educational and informational publication on topics relevant to the prevention, detection, diagnosis, and treatment of thoracic malignancies,” we strive to publish manuscripts of the highest scientific rigor in these areas. Rigorous research requires that studies are thoughtfully conceived, designed, and conducted; with data appropriately analyzed and interpreted; and conclusions meaningfully framed in a context that expands current knowledge.