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- Statistics in Oncology Series
- Dahlberg, Suzanne ERemove Dahlberg, Suzanne E filter
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Statistics in Oncology Series
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- Special Article Statistics in Oncology SeriesOpen Archive
Clinical Versus Statistical Significance in Studies of Thoracic Malignancies
Journal of Thoracic OncologyVol. 15Issue 9p1406–1408Published online: June 21, 2020- Suzanne E. Dahlberg
- Edward L. Korn
- Jennifer Le-Rademacher
- Sumithra J. Mandrekar
Cited in Scopus: 4The scientific synergy between statistics and medical research often leads to controversy when considering statistical versus clinical significance of findings from studies that are neither overwhelmingly practice-changing nor clearly negative. Studies can reach statistical significance but provide evidence that is not clinically meaningful, or results could not be statistically significant but very clinically relevant. To fully appreciate the debate about studies that fall in this gray area, one must understand how to interpret several features of statistical design and the interpretation of results.
