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Journal of Thoracic Oncology

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Issue cover for Volume 10, Issue 4

April 2015

Volume 10Issue 4p537-720, e16-e22

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Acknowledgment of Reviewers

Published in issue: April 2015

p537-538

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In This Issue/Research Watch/News in Brief/News from the IASLC Tobacco Control Committee

In This Issue/Research Watch/News in Brief/News from the IASLC Tobacco Control Committee

Published in issue: April 2015

p539-545

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Editorials

Plasma-Based Tumor Genetics for Monitoring Disease Progression: What Can We Learn from a Tube of Blood?

Philip C. Mack

Published in issue: April 2015

p546-547

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ALK FISH and IHC: You Cannot Have One without the Other

ALK FISH and IHC: You Cannot Have One without the Other

Yasushi Yatabe

Published in issue: April 2015

p548-550

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Comparisons between Mouse and Human Studies Will Help the Prevention, Diagnosis, and Treatment of the Deadliest Type of Lung Cancer

Takashi Kohno,
Motonobu Saito

Published in issue: April 2015

p551-552

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Original Articles

The Comparative Pathology of Genetically Engineered Mouse Models for Neuroendocrine Carcinomas of the Lung

The Comparative Pathology of Genetically Engineered Mouse Models for Neuroendocrine Carcinomas of the Lung

Adi F. Gazdar,
Trisha K. Savage,
Jane E. Johnson,
...
Tyler Jacks,
William D. Travis,
Elisabeth Brambilla

Published in issue: April 2015

p553-564

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High Incidence of Somatic BAP1 Alterations in Sporadic Malignant Mesothelioma

High Incidence of Somatic BAP1 Alterations in Sporadic Malignant Mesothelioma

Masaki Nasu,
Mitsuru Emi,
Sandra Pastorino,
...
Harvey I. Pass,
Haining Yang,
Michele Carbone

Published in issue: April 2015

p565-576

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Supplemental Materials

State of the Art: Concise Review

Stereotactic Ablative Radiotherapy for Centrally Located Early Stage Non–Small-Cell Lung Cancer: What We Have Learned

Stereotactic Ablative Radiotherapy for Centrally Located Early Stage Non–Small-Cell Lung Cancer: What We Have Learned

Joe Y. Chang,
Andrea Bezjak,
Françoise Mornex
on behalf of the IASLC Advanced Radiation Technology Committee

Published in issue: April 2015

p577-585

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Original Articles

Epidemiology/Cost Effectiveness

Cost-Effectiveness of Multiplexed Predictive Biomarker Screening in Non-Small-Cell Lung Cancer

Cost-Effectiveness of Multiplexed Predictive Biomarker Screening in Non-Small-Cell Lung Cancer

Dorothy Romanus,
Stephanie Cardarella,
David Cutler,
Mary Beth Landrum,
Neal I. Lindeman,
G. Scott Gazelle

Published in issue: April 2015

p586-594

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Translational Oncology

ALK Testing in Lung Adenocarcinoma: Technical Aspects to Improve FISH Evaluation in Daily Practice

ALK Testing in Lung Adenocarcinoma: Technical Aspects to Improve FISH Evaluation in Daily Practice

Vittoria Martin,
Barbara Bernasconi,
Elisabetta Merlo,
...
Luca Mazzucchelli,
Fausto Sessa,
Maria Grazia Tibiletti

Published in issue: April 2015

p595-602

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Supplemental Materials

Dynamic Plasma EGFR Mutation Status as a Predictor of EGFR-TKI Efficacy in Patients with EGFR-Mutant Lung Adenocarcinoma

Dynamic Plasma EGFR Mutation Status as a Predictor of EGFR-TKI Efficacy in Patients with EGFR-Mutant Lung Adenocarcinoma

Jeng-Sen Tseng,
Tsung-Ying Yang,
Chi-Ren Tsai,
...
Kang-Yi Su,
Jeremy J.W. Chen,
Gee-Chen Chang

Published in issue: April 2015

p603-610

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Comparison of Methods in the Detection of ALK and ROS1 Rearrangements in Lung Cancer

Comparison of Methods in the Detection of ALK and ROS1 Rearrangements in Lung Cancer

Toni-Maree Rogers,
Prudence A. Russell,
Gavin Wright,
...
Esteban Roberts,
Benjamin Solomon,
Stephen B. Fox

Published in issue: April 2015

p611-618

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Prognostic Impact of Preoperative Tumor Marker Levels and Lymphovascular Invasion in Pathological Stage I Adenocarcinoma and Squamous Cell Carcinoma of the Lung

Prognostic Impact of Preoperative Tumor Marker Levels and Lymphovascular Invasion in Pathological Stage I Adenocarcinoma and Squamous Cell Carcinoma of the Lung

Tomonari Kinoshita,
Takashi Ohtsuka,
Masaya Yotsukura,
...
Katsura Emoto,
Yuichiro Hayashi,
Mitsutomo Kohno

Published in issue: April 2015

p619-628

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Supplemental Materials

Validation of a Multiprotein Plasma Classifier to Identify Benign Lung Nodules

Validation of a Multiprotein Plasma Classifier to Identify Benign Lung Nodules

Anil Vachani,
Harvey I. Pass,
William N. Rom,
...
Paul Kearney,
Kenneth C. Fang,
Pierre P. Massion

Published in issue: April 2015

p629-637

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Prognostic Impact and Clinicopathological Correlations of the Cribriform Pattern in Pulmonary Adenocarcinoma

Prognostic Impact and Clinicopathological Correlations of the Cribriform Pattern in Pulmonary Adenocarcinoma

Arne Warth,
Thomas Muley,
Claudia Kossakowski,
...
Peter Schirmacher,
Hendrik Dienemann,
Wilko Weichert

Published in issue: April 2015

p638-644

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Supplemental Materials

Identification and Validation of Long Noncoding RNA Biomarkers in Human Non–Small-Cell Lung Carcinomas

Identification and Validation of Long Noncoding RNA Biomarkers in Human Non–Small-Cell Lung Carcinomas

Hui Yu,
Qinghua Xu,
Fang Liu,
Xun Ye,
Jialei Wang,
Xia Meng

Published in issue: April 2015

p645-654

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Supplemental Materials

Non-Small Cell Lung Cancer

Final Overall Survival Results from a Phase III, Randomized, Placebo-Controlled, Parallel-Group Study of Gefitinib Versus Placebo as Maintenance Therapy in Patients with Locally Advanced or Metastatic Non–Small-Cell Lung Cancer (INFORM; C-TONG 0804)

Final Overall Survival Results from a Phase III, Randomized, Placebo-Controlled, Parallel-Group Study of Gefitinib Versus Placebo as Maintenance Therapy in Patients with Locally Advanced or Metastatic Non–Small-Cell Lung Cancer (INFORM; C-TONG 0804)

Hongyun Zhao,
Yun Fan,
Shenglin Ma,
...
Mengzhao Wang,
Li Zhang
on behalf of the INFORM investigators

Published in issue: April 2015

p655-664

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Phase II Study of Afatinib, an Irreversible ErbB Family Blocker, in EGFR FISH-Positive Non–Small-Cell Lung Cancer

Phase II Study of Afatinib, an Irreversible ErbB Family Blocker, in EGFR FISH-Positive Non–Small-Cell Lung Cancer

Federico Cappuzzo,
Giovanna Finocchiaro,
Francesco Grossi,
...
Laura Clementi,
Dan Massey,
Armando Santoro

Published in issue: April 2015

p665-672

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Mitosis Trumps T Stage and Proposed International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification for Prognostic Value in Resected Stage 1 Lung Adenocarcinoma

Mitosis Trumps T Stage and Proposed International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification for Prognostic Value in Resected Stage 1 Lung Adenocarcinoma

Edwina Elizabeth Duhig,
Andrew Dettrick,
David Burleigh Godbolt,
...
Kwun Meng Fong,
Belinda Edith Clarke,
Rayleen Veronica Bowman

Published in issue: April 2015

p673-681

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Supplemental Materials

Relationship Between Tumor Size and Survival in Non–Small-Cell Lung Cancer (NSCLC): An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Registry

Relationship Between Tumor Size and Survival in Non–Small-Cell Lung Cancer (NSCLC): An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Registry

Jianjun Zhang,
Kathryn A. Gold,
Heather Y. Lin,
...
J. Jack Lee,
Edward S. Kim,
William N. William Jr.

Published in issue: April 2015

p682-690

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Supplemental Materials

Thymoma

Modified Masaoka Stage and Size Are Independent Prognostic Predictors in Thymoma and Modified Masaoka Stage Is Superior to Histopathologic Classifications

Modified Masaoka Stage and Size Are Independent Prognostic Predictors in Thymoma and Modified Masaoka Stage Is Superior to Histopathologic Classifications

Anja C. Roden,
Eunhee S. Yi,
Sarah M. Jenkins,
...
Randolph S. Marks,
Yolanda I. Garces,
Marie Christine Aubry

Published in issue: April 2015

p691-700

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Conditional Survival of Malignant Thymoma Using National Population-Based Surveillance, Epidemiology, and End Results (SEER) Registry (1973–2011)

Conditional Survival of Malignant Thymoma Using National Population-Based Surveillance, Epidemiology, and End Results (SEER) Registry (1973–2011)

Ellen Kim,
Charles R. Thomas Jr

Published in issue: April 2015

p701-707

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Brief Reports

Transient Hyperesthesia and Radicular Pain: An Unrecognised Complication of Thoracic Radiotherapy

Transient Hyperesthesia and Radicular Pain: An Unrecognised Complication of Thoracic Radiotherapy

David W. Chang,
Claire Phillips,
David Ball

Published in issue: April 2015

p708-712

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A Novel, Highly Sensitive ALK Antibody 1A4 Facilitates Effective Screening for ALK Rearrangements in Lung Adenocarcinomas by Standard Immunohistochemistry

A Novel, Highly Sensitive ALK Antibody 1A4 Facilitates Effective Screening for ALK Rearrangements in Lung Adenocarcinomas by Standard Immunohistochemistry

Kim Gruber,
Martin Kohlhäufl,
Godehard Friedel,
German Ott,
Claudia Kalla

Published in issue: April 2015

p713-716

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Image of the Month

Life-Threatening Bronchomediastinal Fistula Complicating a First Cycle of Chemotherapy in a Stage IV NSCLC Case

Life-Threatening Bronchomediastinal Fistula Complicating a First Cycle of Chemotherapy in a Stage IV NSCLC Case

Sara Piciucchi,
Carlo Gurioli,
Domenico Barone,
...
Giovenzio Genestreti,
Marco Angelo Burgio,
Venerino Poletti

Published in issue: April 2015

p717-718

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Unexpectedly Fludeoxyglucose (18F) Avid Well-Differentiated Adenocarcinoma of the Lung

Unexpectedly Fludeoxyglucose (18F) Avid Well-Differentiated Adenocarcinoma of the Lung

Waleed Brinjikji,
Jennifer M. Boland Froemming,
William P. Holland,
Tobias Peikert,
Geoffrey B Johnson

Published in issue: April 2015

p719-720

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Case Reports

Rapid Response to Trastuzumab Emtansine in a Patient with HER2-Driven Lung Cancer

Rapid Response to Trastuzumab Emtansine in a Patient with HER2-Driven Lung Cancer

Daniela Weiler,
Joachim Diebold,
Klaus Strobel,
Stefan Aebi,
Oliver Gautschi

Published in issue: April 2015

e16-e17

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Novel Association of Elastofibroma with Aortic Stenosis: Report of a Case Report Interfering with a Thoracotomy Procedure and a Reassessment of Typical Patient Demographics and Tumor Location

Novel Association of Elastofibroma with Aortic Stenosis: Report of a Case Report Interfering with a Thoracotomy Procedure and a Reassessment of Typical Patient Demographics and Tumor Location

Barbara Robinson,
Ivayla Geneva,
Steve Landas,
...
Rolfe A. Grage,
Charles Lutz,
William D. Edwards

Published in issue: April 2015

e18-e20

Online Only

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Adding Bevacizumab to Chemotherapy Effectively Control Radioresistant Brain Metastases in ALK-Positive Lung Adenocarcinoma

Adding Bevacizumab to Chemotherapy Effectively Control Radioresistant Brain Metastases in ALK-Positive Lung Adenocarcinoma

Yu-Li Su,

Kun-Ming Rau

Published in issue: April 2015

e21-e22

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