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Editors Choice
1 Results
- Original Article Small Cell Lung CancerOpen Access
Rovalpituzumab Tesirine as a Maintenance Therapy After First-Line Platinum-Based Chemotherapy in Patients With Extensive-Stage–SCLC: Results From the Phase 3 MERU Study
Journal of Thoracic OncologyVol. 16Issue 9p1570–1581Published online: April 3, 2021- Melissa L. Johnson
- Zanete Zvirbule
- Konstantin Laktionov
- Aslaug Helland
- Byoung Chul Cho
- Vanesa Gutierrez
- and others
Cited in Scopus: 35Rovalpituzumab tesirine (Rova-T) is an antibody-drug conjugate targeting DLL3, an atypical Notch ligand expressed in SCLC tumors. We evaluated the efficacy of Rova-T versus placebo as maintenance therapy in patients with extensive-stage–SCLC after platinum-based chemotherapy.