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- Brief ReportOpen Access
Programmed Cell Death Ligand 1 Expression in Untreated EGFR Mutated Advanced NSCLC and Response to Osimertinib Versus Comparator in FLAURA
Journal of Thoracic OncologyVol. 15Issue 1p138–143Published online: October 9, 2019- Helen Brown
- Johan Vansteenkiste
- Kazuhiko Nakagawa
- Manuel Cobo
- Thomas John
- Craig Barker
- and others
Cited in Scopus: 23EGFR mutated (EGFRm) NSCLC tumors occasionally express programmed cell death ligand 1 (PD-L1), although frequency and clinical relevance are not fully characterized. We report PD-L1 expression in patients with EGFRm advanced NSCLC and association with clinical outcomes following treatment with osimertinib or comparator EGFR tyrosine kinase inhibitors in the FLAURA trial (phase III, NCT02296125).