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Editors Choice
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- Original Article Non-Small Cell Lung CancersOpen Access
Postoperative Chemotherapy Use and Outcomes From ADAURA: Osimertinib as Adjuvant Therapy for Resected EGFR-Mutated NSCLC
Journal of Thoracic OncologyVol. 17Issue 3p423–433Published online: November 2, 2021- Yi-Long Wu
- Thomas John
- Christian Grohe
- Margarita Majem
- Jonathan W. Goldman
- Sang-We Kim
- and others
Cited in Scopus: 33Adjuvant chemotherapy is recommended in patients with resected stages II to IIIA (and select IB) NSCLC; however, recurrence rates are high. In the phase 3 ADAURA study (NCT02511106), osimertinib was found to have a clinically meaningful improvement in disease-free survival (DFS) in patients with resected stages IB to IIIA EGFR-mutated (EGFRm) NSCLC. Here, we report prespecified and exploratory analyses of adjuvant chemotherapy use and outcomes from ADAURA.