IASLC Staging Articles
Prognostic Impact of Ground-Glass Opacity/Lepidic Component in Pulmonary Adenocarcinoma: A Hazy Staging DilemmaOne of the most significant modifications that emerged from the eighth edition of TNM in the staging of pulmonary adenocarcinoma (ADC) was the introduction of the concept that only invasive size should be used for the size T-descriptor in part-lepidic nonmucinous ADCs. According to the 2011 International Association for the Study of Lung Cancer, American Thoracic Society/European Respiratory Society, and 2015 WHO lung adenocarcinoma classifications, the lepidic pattern is now regarded as a noninvasive growth pattern.
The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the Forthcoming Eighth Edition of the TNM Classification of Lung CancerThis article proposes codes for the primary tumor categories of adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA) and a uniform way to measure tumor size in part-solid tumors for the eighth edition of the tumor, node, and metastasis classification of lung cancer. In 2011, new entities of AIS, MIA, and lepidic predominant adenocarcinoma were defined, and they were later incorporated into the 2015 World Health Organization classification of lung cancer. To fit these entities into the T component of the staging system, the Tis category is proposed for AIS, with Tis (AIS) specified if it is to be distinguished from squamous cell carcinoma in situ (SCIS), which is to be designated Tis (SCIS).