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In Response: Letter Received From Dr. Tadashi Nishimura Titled “What About Palliative and Supportive Care Landscapes?”

      We thank Dr. Nishumura for his letter reinforcing the importance of palliative and supportive care in thoracic oncology and for giving us the opportunity to clarify the intent of our analysis. As researchers and patient advocates, we cannot overemphasize the importance of integrating palliative care and supportive care in the treatment of patients with lung cancer in the era of modern medicine. As lung cancer has become more molecularly complex, the treatment paradigms for this heterogenous disease have evolved to include new modalities such as targeted therapies and immunotherapies, along with conventional modalities such as surgery, chemotherapy, and radiation. Lung cancer care has become complex and with it, the need to provide more personalized palliative care and support to patients undergoing treatment. Patients receiving immunotherapies have immune-mediated adverse events and nonspecific adverse events such as anemia, fatigue, and nausea.
      • Temel J.S.
      • Petrillo L.A.
      • Greer J.A.
      Patient-centered palliative care for patients with advanced lung cancer.
      Similarly, patients receiving tyrosine kinase inhibitors for biomarker-driven lung cancers may exhibit toxicities such as edema, elevated liver enzymes, dermatologic toxicities, and diarrhea. Newer agents such as lorlatinib are associated with cognitive side effects. These clinical scenarios reiterate the need for the early integration of palliative care and supportive care in lung cancer management.
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      Reference

        • Temel J.S.
        • Petrillo L.A.
        • Greer J.A.
        Patient-centered palliative care for patients with advanced lung cancer.
        J Clin Oncol. 2022; 40: 626-634

      Linked Article

      • What About Palliative and Supportive Care Landscapes?
        Journal of Thoracic OncologyVol. 17Issue 12
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          I am a respiratory physician, but I am also a movie buff. I find the movies in the Marvel Cinematic Universe especially exciting. What makes these films great is that not only they are exciting but also they address social issues. Marvel's films address gender and racial diversity issues and provide a place for people from all walks of life. I think that their films make a social contribution. Their latest film, “Thor Love and Thunder,” focuses on a patient living with cancer. In this movie, the patient chooses to continue her cancer treatment or to take the axe (Mjolnir) to live her life.
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